|
KMID : 0356919940270101448
|
|
Korean Journal of Anesthesiology
1994 Volume.27 No. 10 p.1448 ~ p.1456
|
|
|
Balanced Analgesia with Morphine, Ketorolac and Droperidol in the Treatment of Postoperative Pain in the Gynecologic Patient
|
|
|
|
|
Abstract
|
|
|
Postoperative pain control is one of the main concern for the anesthesiologist. Intermittent narcotic injections caused inadequate pain relief in many patients. Periodic injections could improve analgesia with increased incidence of undesirable
side
effects including respiratory depression, nausea, vomiting, and urinary retenion. Balanced analgesia may lessen these complications without reducing analgesic effect. I assessed the effect of balanced analgesia using morphine, ketorolac and
droperidol.
Each 20 gynecological patients were allocated to one of four groups Morphine(initial bolus 2mg followed by 48mg continousi.v. for 2 days) or ketorolac(initial bolus 30mg, follwed by 120mg continuous i.v. for 2 days)was continuously injected in
group1
and group 2, respectively. In group 3, half doses of morphine and ketorolac in group1, 2 was used in combination. 5mg of droperidol was added to group 3 drugs in group 4. There were no significant changes in blood pressure and heart rate in all
groups.
Onset time of analgesic effect was faster in morphine containing groups I, and 4, and the effect was better in all three morphine containing group 1, 3 and 4 than ketorolac group 2. Untoward effects were least in ketorolac group 2. Droperidol
could
prevent nausea and vomiting, however led to increased incidence of somnolence. It could be concluded that balanced analgesia with morphine, ketorolac and droperidol with fine titration would be better than intravenous morphine or ketorolac alone.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
   
|
|